Database : HANSEN Search on : SARCOMA DE KAPOSI [Subject descriptor] References found : 6 [refine] Displaying: 1 .. 6   in format [Detailed]

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Id: 17964 Author: Gloster HM; Neal K Title: Skin cancer in skin of color Skin cancer in skin of color-v.55 Source: s.l; s.n; 2006. 19 p. ilus, tab. Abstract: Skin cancer is less common in persons with skin of color than in light-skinned Caucasians but is often associated with greater morbidity and mortality. Thus, it is crucial that physicians become familiar with skin cancer in persons of color so as to maximize the likelihood of early detection of these tumors. In dark-skinned ethnic groups, squamous cell carcinoma is most common; squamous cell carcinoma and melanoma usually occur on nonsun-exposed sites; and ultraviolet radiation is not an important etiologic factor for skin cancer with the exception of basal cell carcinoma. Races of intermediate pigmentation, such as Hispanics and Asians, share epidemiologic and clinical features of dark-skinned ethnic groups and Caucasians. Skin cancers pose a significant risk in skin of color and clinicians should focus on preventive measures in these groups such as regular skin exams, self-examination, public education, and screening programs. LEARNING OBJECTIVE: At the completion of this learning activity, participants should be familiar with the epidemiology and unique clinical features of skin cancer in skin of color and be aware of strategies to prevent skin cancer in skin of color.(AU). Descriptors: NEOPLASIAS CUTÂNEAS/quim NEOPLASIAS CUTÂNEAS/compl NEOPLASIAS CUTÂNEAS/diag NEOPLASIAS CUTÂNEAS/genet NEOPLASIAS CUTÂNEAS/imunol NEOPLASIAS CUTÂNEAS/prev NEOPLASIAS CUTÂNEAS/fisiopatol NEOPLASIAS CUTÂNEAS/reabil NEOPLASIAS CUTÂNEAS/radioter NEOPLASIAS CUTÂNEAS/cirurg NEOPLASIAS CUTÂNEAS/terap SARCOMA DE KAPOSI/compl SARCOMA DE KAPOSI/diag SARCOMA DE KAPOSI/fisiopatol - RAIOS ULTRAVIOLETA/uso diag  TERAPIA ULTRAVIOLETA/instrum  TERAPIA ULTRAVIOLETA/métodos Limits: ESTUDO COMPARATIVO HUMANO Location: BR191.1; 00326/cme

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Id: 13963 Author: Okafor, Mark C Title: Thalidomide for erythema nodosum leprosum and other applications ..- Source: s.l; s.n; 2003. 13 p. tab. Abstract: Thalidomide, administered as a sedative and antiemetic decades ago, was considered responsible for numerous devastating cases of birth defects and consequently was banned from markets worldwide. However, the drug remarkably has resurfaced with promise of immunomodulatory benefit in a wide array of immunologic disorders for which available treatments were limited. It is approved by the Food and Drug Administration for erythema nodosum leprosum (ENL). Although the relative paucity of leprosy and ENL worldwide may perceivably limit interest in and knowledge about thalidomide, increasing numbers of new and potential uses expand its applicability widely beyond ENL. Thalidomide, an inhibitor of tumor necrosis factor a, is the best known agent for short-term treatment of ENL skin manifestations, as well as postremission maintenance therapy to prevent recurrence. For this indication, it is effective as monotherapy and as part of combination therapy with corticosteroids. Studies of thalidomide in chronic graft-versus-host disease showed benefit in children and adults as treatment, but not as prophylaxis. The agent has been administered successfully for treatment of cachexia related to cancer, tuberculosis, and human immunodeficiency virus infection, although evidence of efficacy is inconclusive. Thalidomide monotherapy effectively induced objective response in trials in patients with both newly diagnosed and advanced or refractory multiple myeloma. Combination therapy with thalidomide and corticosteroids was also effective in these patients, as well as in treatment of aphthous and genital ulcers. Limited evidence supports the drug's benefit in treatment of Kaposi's sarcoma. Other thalidomide applications include Crohn's disease, rheumatoid arthritis, and multiple sclerosis. Somnolence, constipation, and rash were the most frequently cited adverse effects in studies, but thalidomide-induced neuropathy and idiopathic thromboembolism were critical causes for drug discontinuation. Thalidomide is still contraindicated in pregnant women, women of childbearing age, and sexually active men not using contraception. Clinicians should be conversant with thalidomide in ENL (its primary application) in the natural course of leprosy, as well as in the agent's other applications. (AU). Descriptors: CAQUEXIA/quimioter ERITEMA NODOSO/quimioter DOENCA ENXERTO-HOSPEDEIRO/quimioter HANSENIASE VIRCHOWIANA/quimioter MIELOMA MULTIPLO/quimioter EDUCACAO DO PACIENTE/métodos SARCOMA DE KAPOSI/quimioter TALIDOMIDA/ef adv TALIDOMIDA/uso terap Limits: HUMANO ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 09149/s

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Id: 12316 Author: Geraminejad, Pedram; Memar, Omeed; Aronson, Iris; Rady, Peter L; Hengge, Ulrich; Tyring, Stephen K Title: Kaposi's sarcoma and other manifestations of human herpesvirus 8 ..- Source: s.l; s.n; Nov. 2002. 15 p. ilus, tab. Abstract: Kaposi's sarcoma (KS) was described by Moritz Kaposi in 1872 and was known for an entire century as a rare disorder of older men usually of Eastern European, Mediterranean, and/or Jewish origin. In the early 1980s, the prevalence of KS began to increase dramatically and soon became the most common malignancy in patients with AIDS, especially those who were male homosexuals. In 1994, a new human herpesvirus (HHV) was found to be present in almost 100% of KS lesions. This virus was found to be a gammaherpesvirus, closely related to Epstein-Barr virus, and was designated HHV-8. Subsequently, HHV-8 DNA was found in almost all specimens of classic KS, endemic KS, and iatrogenic KS, as well as epidemic KS (ie, AIDS KS). It is now believed that HHV-8 is necessary, but not sufficient, to cause KS and that other factors such as immunosuppression play a major role. The use of highly active antiretroviral therapy (HAART) since 1996 has markedly reduced the prevalence of AIDS KS in western countries, but because 99% of the 40 million patients with AIDS in the world cannot afford HAART, KS is still a very common problem. Primary effusion lymphoma and multicentric Castleman's disease are also thought to be due to HHV-8. Although HHV-8 DNA has been described in a number of other cutaneous disorders, there is little evidence that HHV-8 is of etiologic significance in these diseases. The mechanism by which HHV-8 causes KS, primary effusion lymphoma, and multicentric Castleman's disease is not well understood but is thought to involve a number of molecular events, the study of which should further our understanding of viral oncology. (J Am Acad Dermatol 2002;47:641-55.) Learning objective: At the completion of this learning activity, participants should be familiar with Kaposi's sarcoma and other manifestations of human herpesvirus 8.. Descriptors: PRODUTOS DO GENE TAT INFECÇOES POR HERPESVIRIDAE HIPERPLASIA DO LINFONODO GIGANTE INTERLEUCINA-6 LINFOMA DE CÉLULA-B LINFOMA DE CÉLULA-B SARCOMA DE KAPOSI SARCOMA DE KAPOSI SARCOMA DE KAPOSI SARCOMA DE KAPOSI TERAPIA ANTI-RETROVIRAL DE ALTA ATIVIDADE FASES DE LEITURA ABERTA/fisiologia HERPESVIRUS 8 HUMANO/fisiologia ESTUDOS SOROEPIDEMIOLOGICOS Limits: HUMANO Location: BR191.1; 0274/cme

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Id: 10326 Author: Matondo, Patrick Title: Clinical classification of African Kaposi's sarcoma: time for reappraisal ..- Source: s.l; s.n; 1995. 2 p. . Descriptors: INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS AFRICA SUSCETIBILIDADE A DOENÇA IMUNIDADE CELULAR ANTIGENO DE MITSUDA HANSENIASE SARCOMA DE KAPOSI SARCOMA DE KAPOSI SARCOMA DE KAPOSI NEOPLASIAS CUTANEAS NEOPLASIAS CUTANEAS NEOPLASIAS CUTANEAS Location: BR191.1; 07176/s

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Id: 10217 Author: Bwire, Robert; Kawuma, H. J. S Title: Leprosy, Kaposi's sarcoma and the acquired immunodeficiency yndrome in two African patients ..- Source: s.l; s.n; 1993. 1 p. . Descriptors: SINDROME DE IMUNODEFICIENCIA ADQUIRIDA SOROPOSITIVIDADE PARA HIV HANSENIASE DIMORFA HANSENIASE TUBERCULOIDE SARCOMA DE KAPOSI Location: BR191.1; 06918/s

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Id: 9184 Author: Drateln, Claudia Reynoso von Title: Sarcoma de Kaposi en un paciente con lepra lepromatosa VIH negativo ?- Source: s.l; s.n; 1994. 3 p. ilus. Descriptors: SARCOMA DE KAPOSI NEOPLASIAS CUTANEAS HANSENIASE LEPROMATOSA PREDNISONA AMILOIDOSE AMILOIDOSE DAPSONA CLOFAZIMINA Location: BR191.1; 06152/s

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